Naprosyn 500mg Tablet


Relief of periarthritis of the shoulder, gout, analgesia, etc.
Active ingredient Naproxen
Estimated delivery days 7~14 days
Target gender Unisex
Pharmaceutical company RPG Life Sciences Ltd

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About Naprosyn 500mg

Highly effective and long lasting! Balanced NSAIDs for different types of pain
  • The effect appears 30 minutes to 1 hour after taking it, and it has an immediate pain-relieving effect.
  • A medium-acting anti-inflammatory analgesic with a single dose that lasts for half a day.
  • Safe for children aged 2 and over.

Naprosyn 500mg is an anti-inflammatory drug manufactured by the Indian pharmaceutical company RPG Lifesciences and is the generic for NIKESUN.

Naprosyn 500mg is a non-steroidal anti-inflammatory drug (NSAIDs), characterized by a formulation that minimizes the excessive immunosuppressive effects and other side effects seen with previous steroidal anti-inflammatory drugs.

Naprosyn 500mg is effective in a wide range of inflammatory diseases, including lumbago, arthralgia, rheumatoid arthritis, and gout pain.

Features of Naprosyn 500mg

The best feature of Naprosyn 500mg is that it has an excellent balance of immediate effect and longevity.

Naproxen, the active ingredient of Naprosyn 500mg, peaks in blood approximately 2 to 4 hours after administration.

This is just the timing when the concentration reaches its maximum value, and in most cases you can actually feel the effect in about 30 minutes to 1 hour after taking it. Due to its fast-acting effect, it can be said to be an analgesic that is suitable for use as a temporary remedy during gout attacks and as a preventive measure against migraine.

Naproxen has a half-life of 14 hours, which is relatively long among non-steroidal anti-inflammatory drugs (NSAIDs).

Although it depends on the symptoms to be indicated, in clinical practice, it is often taken twice a day as a medium-acting type.

Naprosyn 500mg is an easy-to-use anti-inflammatory pain reliever that provides rapid pain relief and long-lasting effects.

It is an easy-to-use non-steroidal anti-inflammatory drug with relatively few side effects.

Anti-inflammatory drugs can be roughly divided into steroidal anti-inflammatory drugs and non-steroidal anti inflammatory drugs including naprosin. Naprosyn 500mg is characterized by having fewer side effects such as excessive immunosuppression than steroidal anti-inflammatory drugs.

Steroidal anti-inflammatory drugs suppress inflammation by suppressing the production of arachidonic acid, which is the raw material of prostaglandins and leukotrienes, which are the causative substances of inflammation. Although it has a very strong anti-inflammatory effect, it has the disadvantage of being susceptible to infections and exacerbating diabetes due to excessive suppression of the immune system.

On the other hand, Naprosin, a non-steroidal anti-inflammatory drug, suppresses the production of prostaglandins by inhibiting the action of enzymes (COX) that produce prostaglandins, thereby suppressing inflammation. The approach to the substance causing inflammation is gentle, and side effects can be kept to a minimum.

However, COX has two subtypes: COX1 is responsible for gastrointestinal protection and COX2 is responsible for inflammation and associated pain.

Naprosyn 500mg does not have COX selectivity, so if it strongly inhibits COX1, it may cause gastrointestinal symptoms such as stomachache and stomach discomfort. When taking Naprosyn 500mg, take it after meals as much as possible to suppress gastrointestinal symptoms as a side effect.

Adapts to different types of pain by adjusting dose and timing

Naprosyn 500mg can be used not only for skeletal and joint pain such as rheumatoid arthritis, but also for severe menstrual pain, low back pain, and pain after injury or after surgery. Naprosyn contains 500mg of the active ingredient (naproxen) per tablet, but the number of tablets and the interval between doses can be adjusted according to symptoms.

Naprosyn 500mg can also be taken by children over the age of two. However, it is recommended to consult a doctor or pharmacist about dosage and administration when taking this medicine for children aged 2 and over and elderly people aged 65 and over.

Effects of Naprosyn 500mg


Rheumatoid arthritis, osteoarthritis, gout attack, ankylosing spondylitis, low back pain, tenosynovitis, shoulder periarthritis, cervico-omo-brachial syndrome, dysmenorrhea, herpes zoster, pain relief and anti-inflammation after trauma, surgery and tooth extraction

Naprosyn 500mg has anti-inflammatory and analgesic effects on various types of pain, including pain in bones and joints typified by rheumatoid arthritis, severe pain during menstruation (dysmenorrhea), and nerve pain caused by herpes zoster. increase. Furthermore, it can be applied not only to the pain caused by these diseases, but also to post-traumatic and postoperative pain, tooth extraction and postoperative pain in dentistry and oral surgery.

However, the effect of Naprosyn 500mg is to suppress only symptoms such as pain and fever, and it is only a symptomatic treatment. Please understand that it is not a medicine that cures the disease itself from the root, and take it appropriately.

How to take Naprosyn 500mg

1 Dose
1 to 3 tablets (250 to 750mg as naproxen) depending on indications
When to take
after meals as much as possible
Number of doses per day
Depending on the indication symptom
Interval between doses
Depending on the indication symptom

About when to take

The timing and dosage of Naprosyn 500mg depends on the indications. Before taking this medicine, consult your doctor or pharmacist about the appropriate dosage and dosage.

For bone and joint pain, including rheumatoid arthritis, for adults, take 1 to 2 tablets at a time, twice daily. The dose can be increased or decreased according to the symptoms, and if sufficient effect is observed, it may be taken once a day. For symptomatic relief of juvenile rheumatoid arthritis in children aged 5 years and older, take 10mg of naproxen per kg of body weight at a time, twice daily.

For dysmenorrhea, start with 2 tablets, then 1 tablet every 6-8 hours. However, do not exceed 5 tablets (1250mg of naproxen) per day.

For gout attacks, start with 3 tablets and then take 1 tablet every 8 hours. Please note that Naprosyn 500mg has the effect of relieving the pain of gout attacks, but it does not treat gout or prevent attacks.

For prevention of migraine, take 3 tablets at the onset of migraine aura symptoms, and continue to take 1 tablet at intervals of 30 minutes or more according to the progress of symptoms. However, do not exceed 5 tablets (1250mg of naproxen) per day.

Active Ingredients of Naprosyn 500mg

The active ingredient naproxen inhibits the production of prostaglandins

One of the substances involved in inflammation that causes pain and fever is a pain-producing substance called prostaglandin. Prostaglandins have the effect of enhancing inflammation, and are substances produced by metabolism by an enzyme called cyclooxygenase (COX).

Naproxen, the active ingredient of Naprosyn 500mg, binds to COX and inhibits its activity, inhibiting the production of prostaglandins.

Naprosyn 500mg side effects

Major side effects

Stomach discomfort (belching), nausea, abdominal pain, stomach pain, rash, edema, etc.

Naprosyn 500mg may cause side effects such as stomach discomfort and nausea due to irritation of the gastric mucosa. If symptoms persist for a long time or worsen, consult your doctor or pharmacist.

Rare side effects

Internal bleeding, muscle spasms, black stools, drowsiness, etc.

Internal bleeding and convulsions are rare, but if these symptoms occur, stop taking Naprosyn 500mg and consult a doctor.

Precautions for Naprosyn 500mg

  • Careful administration
    • People with a history of peptic ulcer
    • Patients with peptic ulcer due to long-term use of non-steroidal anti-inflammatory drugs who require long-term use of naproxen and who are being treated with misoprostol
    • Those who have or have a history of blood abnormalities
    • people with bleeding tendency
    • Those who have or have a history of liver damage
    • People with or a history of renal impairment
    • people with cardiac dysfunction
    • people with hypertension
    • person with bronchial asthma
    • people with ulcerative colitis
    • people with Crohn’s disease
    • Seniors over 65 years old
    • pregnant or breastfeeding
  • Persons who should not take
    • people with peptic ulcer
    • People with severe blood abnormalities
    • People with severe liver damage
    • People with severe renal impairment
    • people with severe heart failure
    • people with severe hypertension
    • People with a history of hypersensitivity to naproxen or other nonsteroidal anti-inflammatory drugs
    • People with aspirin asthma or a history of it
    • late pregnancy
  • Contraindicated drugs
    • Although no specific contraindications have been reported for concomitant use of Naprosyn 500mg, the following drugs require caution when used concomitantly.
    • hydantoin antiepileptic drugs
    • Sulfonylurea hypoglycemic agent
    • anticoagulant
    • antiplatelet agent
    • probenecid
    • methotrexate
    • Antihypertensive agents (β-blockers, diuretics, ACE inhibitors, A-II receptor antagonists, etc.)
    • Lithium formulation
    • Zidovudine
    • New quinolone antibacterial agent
    • Iguratimod
    • Aspirin preparation

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Country of origin

Estimated time of arrival
7-14 days

  • Delivery may be delayed due to weather in the country of origin or holidays of vendors in the country of origin.
  • Delivery may be delayed in some areas such as remote islands and remote islands.

Additional information

Pack Size

300 Tablet/s, 600 Tablet/s


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