Venlor-XR 150mg


Venlor-XR is a serotonin and norepinephrine reuptake inhibitor (SNRI) developed by Cipla and is the generic for Effexor.

The balance between serotonin and norepinephrine maintains mental and physical balance, but when the balance is lost, anxiety and insomnia occur.

This medicine inhibits the reabsorption of serotonin and noradrenaline, increases their concentration in the brain, and improves anxiety, depressed mood, and decreased motivation/energy.

Increased relaxation, motivation and energy
Active ingredient Venlafaxine
Estimated delivery days 7~14 days
Target gender unisex
Pharmaceutical company Cipla

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Features of Venlor-XR 150mg

It is a fourth-generation antidepressant with relatively few side effects that treats depression and anxiety disorders.
  • Selectively maintains brain levels of neurotransmitters involved in depressive symptoms.
  • It is an antidepressant with relatively few side effects.
  • It can be used economically because it is a generic drug.


  • depression
  • Stabilization of restless mental state ※If you feel uncomfortable, you can change it

Venlor-XR is a drug that increases the concentration of both serotonin and noradrenaline in the brain, and the ratio of action is said to be about 1 for noradrenaline and 30 for serotonin. Therefore, Venlor-XR is a drug that can be expected to increase serotonin and noradrenaline.

Due to these effects, it is effective when used in depression, when anxiety and depression are strong and accompanied by a decrease in motivation.

About Venlor-XR 150mg

Venlor-XR is a fourth-generation antidepressant that inhibits the reuptake of serotonin and norepinephrine. By reducing the reuptake amount of serotonin and noradrenaline, it is possible to improve depressive symptoms and anxiety disorders by maintaining the concentration of serotonin and noradrenaline in the brain.

The main ingredient is venlafaxine, which is said to be highly effective for moderate to severe depression and has few side effects, making it easy to take.

In addition, it is a generic drug of Effexor, which is the original drug, and can be purchased at about 1/5 the price of the original drug, so it can be used economically.

Improves depressive symptoms by maintaining neurotransmitter levels

The neurotransmitters serotonin and norepinephrine are involved in depression. Serotonin is a substance that gives people a sense of security and makes them feel relaxed. On the other hand, noradrenaline is a substance that controls motivation, activity, aggressiveness, thinking ability, and concentration. Fall into depression. Depression is thought to cause various symptoms when these substances become insufficient due to stress, etc.

Venlafaxine, the active ingredient of Venlor-XR, mainly inhibits the reabsorption of serotonin and noradrenaline, and can maintain the concentration of serotonin and noradrenaline in the brain at a certain level. It also has the effect of maintaining dopamine levels, albeit slightly, by inhibiting the reabsorption of dopamine, which is involved in pleasure and positive emotions.

Changes in Antidepressants

Since the development of iproniazid as the first antidepressant in 1952, various antidepressants that are effective against depressive symptoms and have few side effects have been developed and improved. These drugs are classified according to the structure and effect of the active ingredient, and are currently called 1st to 4th generation drugs.

First, tricyclic drugs, including iproniazid, were developed as the first generation. While these have definite antidepressant effects, side effects include anticholinergic effects (dry mouth and constipation) and cardiotoxicity that adversely affects the heart.

Next, improved tricyclic, tetracyclic, and bicyclic systems appeared as the second generation, and although the antidepressant effect was slightly weaker than the first generation, anticholinergic effects and cardiotoxicity were less than the first generation. it was done.

After that, SSRIs (selective serotonin reuptake inhibitors) will appear as the third generation. The antidepressant effect of the 3rd generation is slightly weaker than that of the 2nd generation, but the anticholinergic effects and cardiotoxicity are greatly reduced. Then, SNRIs (serotonin and noradrenaline reuptake inhibitors) were developed as the fourth generation, with antidepressant effects comparable to the first generation and side effects comparable to the third generation.

Venlor-XR is classified as a 4th generation SNRI antidepressant among these.

The drug has relatively few side effects

Venlafaxine, the active ingredient in Venlor-XR, is effective in treating depression and anxiety disorders. On the other hand, side effects are rare, but you may experience side effects such as drowsiness, headache, and dry mouth. Also, it cannot be used in combination with other antidepressants. After taking this medicine, pay attention to changes in your physical condition and if the symptoms are severe, consult a doctor.

How to take Venlor-XR 150mg

1 Dose
1 tablet or 1/2 tablet (37.5mg as “Venlafaxine”)
Number of doses per day
up to 1 time
Upper limit

It is best to take it at the same time every day

The initial dose of Venlor-XR is 37.5mg, and after 1 week or longer of continuous use, the dose can be increased to 75mg daily, up to a maximum of 225mg. There is no rule about when to take the medicine before or after meals.

Venlor-XR 150mg Side Effects

Major side effects
  • nausea
  • Abdominal discomfort (abdominal pain, bloating, constipation, etc.)
  • somnolence
  • dizzy
  • dry mouth
  • headache
  • rash
  • pruritus
  • hives
  • Angioedema
  • photosensitivity reactions, etc.
Rare side effects
  • serotonin syndrome
  • malignant syndrome
  • Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
  • QT prolongation
  • ventricular tachycardia
  • ventricular fibrillation
  • spasm
  • Anaphylaxis
  • Toxic epidermal necrolysis
  • rhabdomyolysis
  • agranulomatosis
  • aplastic anemia
  • Pancytopenia
  • fewer good shots
  • decreased platelet count
  • interstitial lung disease
  • hypertensive crisis
  • urinary retention, etc.

Precautions for Venlor-XR 150mg

Careful administration
The following people should be careful when taking this medicine.

  • Those with mild to moderate liver dysfunction
  • Those with mild to moderate renal dysfunction
  • Patients with bipolar disorder
  • Those with a history of suicidal ideation or attempted suicide
  • Those who are predisposed to organic brain disorders or schizophrenia
  • Those with comorbid disorders with high impulsivity
  • Convulsive diseases such as epilepsy, or those with a history of these
  • Those with glaucoma or increased intraocular pressure
  • Those with high blood pressure or heart disease
  • Those with QT prolongation or a history of it
  • Those taking drugs known to cause QT prolongation
  • Those with marked bradycardia or hypokalemia
  • Patients concomitantly taking drugs that increase the risk of bleeding, those with bleeding tendency or bleeding predisposition
  • Those who have difficulty urinating due to an enlarged prostate, etc.
  • Elderly people (65 years old and over)
  • Those who are pregnant or may become pregnant
  • breastfeeding
Persons who should not take
The following people cannot use this medicine.

  • Those with a history of hypersensitivity to Venlor-XR 150mg ingredients
  • Those who are on monoamine oxidase (MAO) inhibitors or within 2 weeks after discontinuation
  • Those with severe liver dysfunction (Child-Pugh classification C)
  • Patients with severe renal dysfunction (glomerular filtration rate less than 15mL/min) or those on dialysis
Precautions for combined use
Caution should be exercised when using this medicine in combination with the following medicines.

  • alcohol (drinking)
  • Methylthioninium chloride hydrate (methylene blue)
  • Serotonin agonists, lithium carbonate, serotonin/noradrenaline reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs), tramadol hydrochloride, triptans, L-tryptophan-containing preparations, linezolid, etc.
  • St. John’s wort-containing foods, etc.
  • adrenaline, noradrenaline
  • Drugs that increase bleeding tendency
  • Haloperidol
  • Imipramine
  • Cimetidine
  • CYP3A4 inhibitors (ketoconazole, erythromycin, ritonavir, etc.)
  • Metoprolol
  • Indinavir
  • Risperidone
Contraindications for co-administration
Avoid using this medicine in combination with the following medicines.

  • monoamine oxidase (MAO) inhibitor
  • Selegiline hydrochloride (FP)

How to store Venlor-XR 150mg

  • Avoid direct sunlight and store at room temperature.
    It does not need to be refrigerated, but should not be stored in a hot or humid place.
  • Keep out of reach of small children.
    Please store it carefully so that children do not take it by mistake.


Country of origin

Estimated time of arrival
7-14 days

  • Delivery may be delayed due to weather in the country of origin or holidays of vendors in the country of origin.
  • Delivery may be delayed in some areas such as remote islands and remote islands.

Additional information

Pack Size

100 Tablet/s, 200 Tablet/s, 300 Tablet/s


Cipla Ltd.


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