Tofisern 50mg Tablet


Tofisern is an autonomic nerve regulating agent developed by Concern Pharma and is a generic drug of Grandaxin. It is a benzodiazepine anti-anxiety drug similar to Depas and Silase.

The autonomic nervous system is very important, and symptoms such as autonomic imbalance, menopause, and ovarian deficiency occur when the balance of the autonomic nervous system is disrupted due to abnormalities in hormones and neurotransmitters.

Improvement of autonomic imbalance, menopausal disorders, etc.
Active ingredient Tofisopam
Estimated delivery days 7~14 days
Target gender unisex
Pharmaceutical company Concern Pharma

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About Tofisern 50mg

Balance your autonomic nerves and live a comfortable life without anxiety!
  • It is highly effective and you can feel the effect quickly!
  • Less addictive and can be tapered off gradually.
  • Less side effects!

Tofisern is an autonomic neuromodulator and is a generic drug for Grandaxin. When you take Tofisern, the active ingredients act to regulate the autonomic nerves, and improve a wide range of autonomic nerve symptoms such as headaches, dull headaches, malaise, and depression.

The autonomic nervous system plays a very important role in the body, and when it is disturbed, it causes symptoms such as autonomic imbalance, menopause, and ovarian deficiency.

There are two types of autonomic nervous system: the sympathetic nervous system and the parasympathetic nervous system. The sympathetic nervous system becomes active during the daytime when the body is active, and the parasympathetic nervous system becomes active during the nighttime when the body is relaxed.

If the balance between these two is good, the mental and physical condition will be adjusted, but if the balance is lost, the mental and physical condition will be disturbed.

Tofisern is a drug that stabilizes the balance of this autonomic nervous system.

Features of Tofisern 50mg

As mentioned above, it is important to have a balance between the sympathetic and parasympathetic nerves for the condition of the mind and body. If the sympathetic nerves act strongly, the blood pressure rises, the pupils dilate, and the mind and body become excited. Also, if the parasympathetic nerves act strongly, the blood pressure drops, the pupils close, and the mind and body enter a state of rest.

Tofisern works well on this autonomic nervous system and is effective for anxiety, fatigue, depression, and sweating. It also has the advantage of being a highly safe drug with few side effects.

It is highly effective and you can feel the effect quickly!

Currently, most of the anti-anxiety drugs aimed at stabilizing the autonomic nervous system and mental health are called “benzodiazepines”.

Tofisern is also a benzodiazepine drug, but unlike other benzodiazepines, it acts on the hypothalamus of the brain, so it has the characteristic of acting on disturbances of the autonomic nervous system. It is also known for its high efficiency.

If the autonomic nerves are disturbed, symptoms such as anxiety, headaches, depression, and sweating may appear on the surface. In such a case, most people would like to return to the original state as soon as possible.

I think there are people who don’t want to be taken care of by their surroundings. Even in such a case, the immediate effect of Tofisern is useful.

The peak effect of Tofisern is about 1 hour after administration, and the duration of action is about 3-6 hours. I think that even in an emergency situation where you want to get out of a painful condition right away or want to feel better, you can feel that your symptoms will be relieved.

Less addictive and can be tapered off gradually

I sometimes see bad reviews on the Internet and SNS, such as “If you start taking autonomic nerve regulating drugs and anti-anxiety drugs, you will become addicted and you will not be able to stop.” It is true that if you continue to take the drug for a long time, you may suddenly experience withdrawal symptoms such as irritability, anxiety, and sweating when you stop taking the drug.

However, this is the case when the dosage is increased by self-judgment, or when a drug with a long action time and strong action is used regularly. If you take it correctly, it won’t happen. Rather, it can be said that it is a useful medicine if taken properly.

It may be easier to understand if you imagine alcohol. It is true that people who drink a lot and continue to drink tend to become alcoholics. That’s not the case though.

Tofisern has an immediate effect, but the after effect is mild. If you follow the directions, you will be able to gradually taper off the dose without becoming dependent.

Effects of Tofisern 50mg


  • depression
  • restless mental stability

Modern people are able to lead a comfortable life due to the development of science and technology, but on the other hand, the rhythm of life tends to be disturbed in a competitive society, and few people lead an irregular life with day and night reversed.

There is none. As a result, many people are living with stress, and it is said that the autonomic nervous system is easily disturbed. Disturbances in the autonomic nervous system exhaust the mind and body.

This Tofisern has the effect of stabilizing the disturbed autonomic nerves. Tofisern stabilizes the autonomic nervous system by acting on the brain, and relieves symptoms such as headache, dizziness, anxiety, depression, and loss of motivation.

In clinical trials, the efficacy of Tofisern in autonomic imbalance and menopausal disorders has been found to be more than 80%, and it can be said that it is a reliable agent for adjusting the balance of the autonomic nervous system.

Others may also be prescribed to treat hyperhidrosis, as it stabilizes the sympathetic nervous system.

How to take Tofisern 50mg

1 Dose
1 tablet (50mg as “tofisopam”)
Number of doses per day
Up to 3 times * Adjust accordingly depending on age and symptoms
Upper limit of dosage

Less side effects!

Tofisern is fast-acting, but has a short duration of action, and is thought to have few side effects. In actual clinical trials, only 2.6% of those who took the drug experienced side effects. Side effects include drowsiness, lightheadedness, dry mouth, vomiting, loss of appetite, constipation, abdominal pain, and fatigue.

If you feel any change, please consult your doctor immediately. Also, be sure to follow the usage and dosage so as not to increase dependence.

About the active ingredient of Tofisern 50mg

Active ingredient Tofisern 50mg

The active ingredient, Tofisern, acts on the hypothalamus in the brain, unlike ordinary benzodiazepines. The hypothalamus is an integrated center that controls the regulation of endocrine and autonomic functions, and is composed of many nerve nuclei, and controls many functions such as temperature regulation, stress response, eating, and sleep.

The hypothalamus is an important place in the brain that plays a role in maintaining the human mind and body by balancing the sympathetic and parasympathetic nerves.

Until now, many benzodiazepine drugs acted on the limbic system, which is related to drowsiness and relaxation, but Tofisern, which is also a benzodiazepine, is highly effective for autonomic imbalance and menopausal disorders. It’s for this reason.


Country of origin

Estimated time of arrival
7-14 days

  • Delivery may be delayed due to weather in the country of origin or holidays of vendors in the country of origin.
  • Delivery may be delayed in some areas such as remote islands and remote islands.

Additional information

Pack Size

100 Tablet/s, 150 Tablet/s, 50 Tablet/s


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