Trazalon 50mg Tablet


Trazalon 50mg is a serotonin blocking reuptake inhibitor (SARI) developed by Sun Pharma and the generic drug for Desirel.

This medicine increases the amount of serotonin in the brain, which has decreased, to calm the excitement of the brain and induce drowsiness.

Effect Improvement of depression
Active ingredient Trazodone
Estimated delivery days 7~14 days
Target gender unisex
Pharmaceutical company Sun Pharma

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Characteristics of Trazalon 50mg 

Serotonin Blocking Reuptake Inhibitor Relieves Depressive Mood and Helps with Insomnia
  • An antidepressant that relieves depression and increases motivation through anti-anxiety and sedative effects.
  • It also has the effect of deepening sleep, making it ideal for depression with insomnia.
  • Safe to use with low risk of addiction, tolerance and side effects.


  • Improvement of depression and depressive symptoms.
  • improvement of insomnia.

Trazalon is effective in improving depression and insomnia.

Depression develops when there is less serotonin in the brain, and Trazalon works by inhibiting the reuptake of serotonin. This increases the concentration of serotonin in the brain and has the effect of improving depression.

However, there are reports that treatment results are poor for those with severe or moderate depression, so depending on the symptoms, it is necessary to consider the choice of other antidepressants.

It also has adrenergic receptor (α1) and histamine receptor (H1) blocking effects. Because of its drowsiness-inducing effect, it is sometimes used as a treatment for insomnia. It is commonly used to treat depression and insomnia, but it is said to be effective for generalized anxiety disorder, bulimia nervosa, agitation associated with dementia, obsessive-compulsive disorder (OCD), and delirium. There are also reports.

However, clinical trials have shown no difference from placebo, and it is difficult to adjust the dosage, so if you use it for these symptoms, please consult your doctor before using it.

About Trazalon 50mg 

Trazalon is an antidepressant manufactured by Sun Pharma, a major Indian pharmaceutical company.

It is classified as a serotonin blocking reuptake inhibitor (SARI) and works by increasing serotonin levels in the brain. As a result, it has the effect of relieving depression and anxiety caused by depression and increasing motivation.

It is also used as a sleep aid because of its antihistamine effect and its ability to induce drowsiness.

In general, it is said that it does not have the strong effects of tricyclic antidepressants, but there is little risk of side effects, dependence, tolerance, etc., and it is effective for relatively mild depression accompanied by anxiety and insomnia. It is suitable. The active ingredient, trazodone, was originally synthesized in Italy in the 1970s and approved for treatment in the United States in the 1980s.

It is an antidepressant with a long history of use in USA since 1991. Since Trazalon is a generic drug, it has the same effects, ingredients, and side effects, but it has the advantage of being able to continue treatment while keeping treatment costs down.

It is recommended for those who want to reduce the risk of tolerance and side effects with the cheapest possible medicine and improve relatively mild depression, anxiety, and insomnia symptoms.

Best antidepressant for not only depression but also for improving insomnia

Trazalon is an antidepressant that improves depression and anxiety by increasing the concentration of serotonin.

They are generally considered to be less effective than tricyclic antidepressants, but some believe they are equally effective.

As selective serotonin reuptake inhibitors (SSRIs) have become mainstream antidepressants, their use is decreasing, but they are effective in treating mild depression.

In recent years, it has been increasingly used as a sleeping drug by taking advantage of drowsiness due to its antihistamine action. Tolerance and dependence may be a problem with benzodiazepine receptor agonist sleeping pills, and many people may hesitate to take them.

There are various symptoms of insomnia, but it is said that it is particularly effective for waking up in the middle of the day and early morning awakening.

In addition, when it was used for insomnia associated with PTSD, more than 90% reported that falling asleep improved. It is an antidepressant recommended for those who are depressed and have particularly strong insomnia symptoms, or for those who are concerned about tolerance or dependence due to insomnia such as waking up in the middle of the night or early morning awakening.

Treatment is possible with reduced risk of addiction, tolerance, side effects, etc.

Antidepressants and sleeping pills are drugs that tend to be taken for a long time. Therefore, there are concerns about side effects, the formation of tolerance, and addiction.

However, it is painful to worry about it and not be able to improve the symptoms forever. Among antidepressants, Trazalon has the advantage of having less risk of side effects, tolerance, and addiction.

It is said that many people hesitate to take antidepressants and sleeping pills due to these problems, but with Trazalon, it is possible to treat with almost no worries.

Side effects may be a little stronger when you start taking them or when you increase the dose, but they are still mild compared to SSRIs.

In particular, many people may be concerned about sexual dysfunction caused by SSRIs, but it is said that this possibility is low with Trazalon.

In addition, it is an antidepressant that is easy to use even for the elderly, although we must be careful about side effects such as lightheadedness. If you are worried about dependence or side effects and cannot take antidepressants or sleeping pills, please try Trazalon, which has less risk.

Improving depressive state by inhibiting the recovery of serotonin to nerve cells

Depression is caused by a lack of serotonin in the brain, so increasing the amount of serotonin in the brain can improve depression.

Information is transmitted by releasing serotonin between nerve cells, but serotonin that has been released too much is recovered by nerve cells again. At this time, if serotonin is recovered into nerve cells, the amount of serotonin involved in information transmission will decrease accordingly.

Trazodone works by blocking the process by which serotonin is returned to nerve cells. As a result of this action, the amount of serotonin increases, so it becomes possible to improve depression.

How to take Trazalon 50mg 

1 Dose
1 to 4 tablets (75 to 200mg as trazodone)
Number of doses per day
1 to multiple times

Take 75-100mg daily with water or lukewarm water. Depending on the situation, the dose may be increased up to 200mg a day, but do not take it all at once.

The dosage may be adjusted according to the age and symptoms. If the effect or side effects are strong, adjust the tablet by half or quarter.

Precautions when taking

Since the dose of Trazalon varies from person to person, start with a small amount.

Keep an eye on it and if it doesn’t seem effective, increase the amount. The effect is not immediate, so it may take 2 to 3 weeks or even longer to see results.

Even if your symptoms improve, do not stop taking this medicine on your own and consult your doctor. Although there are individual differences, it is recommended to continue taking it for about six months to two years.

This medicine may cause drowsiness, decreased attention/concentration/reflex movement ability, etc. Do not engage in dangerous work such as driving a car or working at heights.

In addition, since side effects such as dry mouth are likely to occur, rinse your mouth with water. Lightheadedness can also be a side effect, so don’t stand up suddenly and move slowly.

Side effects of Trazalon 50mg 

Major side effects

  • sleepiness
  • dry mouth
  • constipation
  • Dizziness and lightheadedness
  • palpitations
  • trembling hands
  • Low blood pressure
  • itch
  • rash, etc.

Trazalon is one of the antidepressants with the fewest side effects. If the symptoms of side effects are mild, there is not much of a problem, but if the symptoms are severe, consult a doctor as soon as possible.

Side effects are more likely to occur when you have just started taking this medicine or when the dosage is increased.

Rare side effects

  • malignant syndrome
  • Delirium/Confusion
  • serotonin syndrome
  • severe arrhythmia
  • paralytic ileus
  • Severe blood component abnormalities
  • Persistent erection of the penis and clitoris, etc.

Mental changes such as agitation, anxiety, restlessness, and high mood may also occur as side effects.

Side effects such as those mentioned above rarely occur, but if you feel anything unusual, please consult your doctor immediately.

Precautions for Trazalon 50mg 

Careful administration
The following people should be careful when taking this medicine.

  • person with glaucoma
  • People who have difficulty urinating (benign prostatic hyperplasia)
  • person with heart disease
  • epileptic person
  • manic-depressive person
  • People with predisposition to schizophrenia, high impulsiveness and psychiatric symptoms
  • senior citizen
  • under 24 years old
  • suicidal person
  • breastfeeding person
  • pregnant or possibly pregnant
Persons who should not take
The following people cannot use this medicine.

  • People who are allergic to active ingredients
  • Patients receiving saquinavir mesylate
Contraindications for co-administration
Avoid using this medicine in combination with the following medicines.

  • alcohol
  • Central nervous system depressants (barbituric acid derivatives, etc.)
  • Antihypertensive
  • monoamine oxidase inhibitor
  • Cardiac glycosides (digoxin, etc.), phenytoin
  • Phenothiazine derivatives (chlorpromazine, etc.)
  • Warfarin
  • carbamazepine
  • CYP3A4 inhibitors (ritonavir, indinavir)
  • tandospirone, paroxetine, amitriptyline

How to store Trazalon 50mg 

  • Store at room temperature, avoiding direct sunlight and high temperature and humidity.
    It does not need to be refrigerated and should be kept at room temperature away from direct sunlight, heat and humidity.
  • Keep out of reach of children.
    Avoid the possibility of taking it by mistake.


Country of origin

Estimated time of arrival
7-14 days

  • Delivery may be delayed due to weather in the country of origin or holidays of vendors in the country of origin.
  • Delivery may be delayed in some areas such as remote islands and remote islands.

Additional information

Pack Size

100 Tablet/s, 200 Tablet/s, 300 Tablet/s


Sun Pharmaceutical


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